Open-Source Packages. Validated by Us, Ready for You.
Package and dependency management is one of the biggest blockers to running R at scale in a regulated environment. Teams spend months building validation frameworks, managing version changes, and assembling submission evidence — before a single analysis runs. And once built, the maintenance burden doesn’t stop.
OpenVal removes it. OpenVal is a clinical research solution for validated open-source statistical packages — a subscription library of validated, GxP-ready open-source R packages, every one reviewed, tested, and documented by Atorus engineers, and re-validated as versions change. Your team gets a trusted, reproducible foundation from day one, not a project.
700+ packages. Already validated. No validator needed.
Most validation frameworks give you the process — your team still runs it. With OpenVal, the validation has already happened. As OpenVal reaches 700+ packages, every one has been risk assessed, tested to mitigate that risk, reviewed, and documented by Atorus engineers.
Your team doesn’t need a validator. They need a subscription.
Why Teams Choose Subscription Over Building It Themselves
Building your own validation framework sounds like control. In practice, it means months of engineering effort before a single package is validated, an ongoing maintenance burden as versions change, and submission risk that sits entirely with your team.
With OpenVal, that work has already been done by Atorus. 80,000+ hours of validation work, 14,000+ tests, and 1,100+ re-validations — and growing — so your team inherits a trusted, submission-ready foundation from day one, not a process they have to stand up, staff, and sustain.
OpenVal Is Your Reliable Source of Truth
OpenVal’s validated packages are the product of broad industry collaboration, and each package is tested and reviewed for absolute dependability.
Proven in Practice
6 Regulatory Submissions Successfully Supported
OpenVal delivers the reproducible environment and validation evidence regulatory agencies require. With a track record of supporting real submissions, OpenVal provides more than promises — it delivers proof.
Why Should Teams Choose OpenVal?
700+
open-source R packages, validated and ready to use from day one
1,100+
re-validations handled as package versions change — no maintenance burden on your team
6
regulatory submissions with leading pharma sponsors
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Reproducible, version-locked environments that meet GxP standards
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Validation evidence and installation documentation included
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Predictable subscription cost replacing in-house validation staffing
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From exploratory to submission-ready, one trusted library
What Others Are Saying
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“I’m excited that Atorus supports Bayer in the setup and maintenance of our validated R environment. The implementation of OpenVal has helped us to further streamline our processes and stay up to date with state-of-the-art statistical methodology in open-source packages.”
VP Global Head Of Statistical Programming and Analytics 
How Does OpenVal Validate Every Package?
Every package in OpenVal goes through the same rigorous process — no exceptions, no shortcuts:
Function-Level Testing
Reproducible Installation Tools
Source Code Traceability
Still have questions about OpenVal? Explore our FAQ or discover more with the OpenVal packages list, release notes, cheat sheet, and our clinical programming case study.
OpenVal vs Building It Yourself
| OpenVal | Building It Yourself | |
|---|---|---|
| Model | Subscription. | Build a framework in-house or implement a third-party tool, then operate it to validate packages yourselves. |
| Time to Value | Immediate. Validated packages and evidence available on day one. | 3+ months before a single package is validated. |
| Internal Effort | No validation lift. 80,000+ hours and 14,000+ tests already invested for you, with hundreds of packages and system dependencies bundled and ready to deploy. | Your teams run validation execution, dependency management, documentation, and audit readiness. The full engineering and operational burden sits with you. |
| Maintenance | Handled for you, with 1,100+ re-validations as package versions change. | Ongoing version churn becomes your team’s recurring responsibility. |
| Proof | 6 regulatory submissions supported, trusted by pharma and biotech partners. | A process your team would be standing up for the first time, adding risk at the time of submission. |
| Cost | Predictable, a known annual line item. | Build or license costs plus ongoing internal staffing to operate. |
The engineering is done. The evidence is ready. Your team can start today.